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Study Searching For ‘Most Promising’ Ebola Vaccine
By Stephen N. Sonpon
MONROVIA, April 7 (LINA) –The Partnership for Research on Ebola Virus in Liberia (PREVAIL) has embarked upon a vaccine study to find the most promising to prevent or quickly control future Ebola outbreaks.
The study is also to assess the safety and ability of three different Ebola vaccine strategies in order to stimulate an immune reason to the virus that may be protective, according to the Principal Investigator for PREVAIL Vaccine, Mark S. Kieh.
Addressing the Ministry of Information regular press briefing at the ministry Thursday, Kieh said the first part of the study will enroll up to 600 people 12 years and older.
He added that the second part is expected to start in the second half of 2017 and aims to enroll 4,900 people, including 3,500 healthy men and women aged 18 and older.
Kieh noted that 1,400 children will be enrolled during the third study the same year.
He said the key goals are to determine how quickly immune responses to the vaccines are generated, how strong the immune response is and how long it lasts.
According to him, the study will continue to monitor the safety of the test vaccine in the adults and carefully test their safety record in children, a population vulnerable to Ebola.
Kieh indicated that of the three vaccines, two are real vaccines and the other is salt water, adding “nobody knows the type they are getting, not even the nurse or study physician.”
He noted there is no risk to participants becoming infected with Ebola as the vaccines only has a protein of the virus, not the whole virus.
He stated that some people are not eligible to join the study, including people who have fever, Ebola, and women who are breastfeeding.
“The second part the study will evaluate all three vaccination strategies, including two additional prime boost strategies involving the Merck vaccine” kieh noted.
The Ebola virus disease claimed the lives of over 4,000 in the three Mano River countries of Liberia, Guinea and Sierra Leone in 2014.